Copure SPE (HLB family)
Biocomma Copure HLB: PS/DVB copolymer, pH 0–14, 500–750 m²/g, 200–400 Å, cartridges from 30 mg/1 mL to 500 mg/12 mL.
View product
Reference: HC8536 / HC8436 / HC8434
CommaSil® C8 HPLC Column
A C8 reversed-phase HPLC column on high-purity silica with complete capping, giving somewhat lower retention than C18 for compounds of moderate to high hydrophobicity; 3, 3.5 and 5 μm particles.
Key specifications
- Phase
- C8 on high-purity silica microspheres, fully capped
- Retention vs C18
- Slightly weaker retention capacity, classical reversed-phase retention and selectivity
- Particle sizes
- 3, 3.5 and 5 μm
- Column internal diameters
- 2.1, 3.0 and 4.6 mm
- Configured to your application by our specialists
- Installed and commissioned on site
- Training and after-sales support across Jordan, the GCC and MENA
CommaSil® C8 HPLC Column
Request a quoteOverview
Product overview
CommaSil® C8 is made from high-purity silica microspheres, using a distinctive surface bonding and complete capping process to minimize silanol activity.
Compared with a C18 column, its retention capacity, classical reversed-phase retention and selectivity are slightly weaker, which makes it more suitable for the separation of compounds with moderate or high hydrophobicity.
The page's application example is the determination of mycophenolate mofetil related substances (UV 250 nm). Particle sizes of 3, 3.5 and 5 μm are available in 2.1, 3.0 and 4.6 mm internal diameters.
Specifications
Technical specifications
9 parameters
Column
- Phase
- C8 on high-purity silica microspheres, fully capped
- Retention vs C18
- Slightly weaker retention capacity, classical reversed-phase retention and selectivity
- Particle sizes
- 3, 3.5 and 5 μm
- Column internal diameters
- 2.1, 3.0 and 4.6 mm
- Column lengths
- 30, 50, 100, 150 and 250 mm (250 mm in 3.0 and 4.6 mm i.d.)
Application example
- Example: mycophenolate mofetil related substances
- 250 × 4.6 mm, 5 μm (HC8536); UV 250 nm; 1.5 mL/min; 45 °C; 10 μL; triethylamine buffer pH 5.3 / acetonitrile 65:35
Ordering information
- Catalog numbers, 3μm particles
- 30×2.1mm HC8114; 50×2.1mm HC8214; 100×2.1mm HC8314; 150×2.1mm HC8414; 30×3.0mm HC8124; 50×3.0mm HC8224; 100×3.0mm HC8324; 150×3.0mm HC8424; 250×3.0mm HC8524; 30×4.6mm HC8134; 50×4.6mm HC8234; 100×4.6mm HC8334; 150×4.6mm HC8434; 250×4.6mm HC8534
- Catalog numbers, 3.5μm particles
- 30×2.1mm HC8115; 50×2.1mm HC8215; 100×2.1mm HC8315; 150×2.1mm HC8415; 30×3.0mm HC8125; 50×3.0mm HC8225; 100×3.0mm HC8325; 150×3.0mm HC8425; 250×3.0mm HC8525; 30×4.6mm HC8135; 50×4.6mm HC8235; 100×4.6mm HC8335; 150×4.6mm HC8435; 250×4.6mm HC8535
- Catalog numbers, 5μm particles
- 30×2.1mm HC8116; 50×2.1mm HC8216; 100×2.1mm HC8316; 150×2.1mm HC8416; 30×3.0mm HC8126; 50×3.0mm HC8226; 100×3.0mm HC8326; 150×3.0mm HC8426; 250×3.0mm HC8526; 30×4.6mm HC8136; 50×4.6mm HC8236; 100×4.6mm HC8336; 150×4.6mm HC8436; 250×4.6mm HC8536
Features
Key features
- 01
Complete capping
Surface bonding and complete capping minimize silanol activity.
- 02
Moderate retention
Weaker retention than C18, suited to moderately or highly hydrophobic compounds.
- 03
Three particle sizes
3, 3.5 and 5 μm.
From order to operation
We stay with the instrument after it arrives
Al-Shaker specifies the configuration, documents the system, and supports it across Jordan, the GCC, and MENA.
- 01
Consult
- 02
Plan
- 03
Supply
- 04
Install
- 05
Train
- 06
Support
Keep exploring
More from Biocomma
Copure QuEChERS
Biocomma Copure QuEChERS: EN 15662, AOAC 2007, and Original salts in 50 mL tubes — AOAC 6 g MgSO4 + 1.5 g NaOAc; EN 4 g MgSO4 + 1 g NaCl + citrates.
View product
CommaSil HPLC columns
Biocomma CommaSil fully porous silica HPLC: 3 / 3.5 / 5 μm particles, 2.1 / 3.0 / 4.6 mm IDs, lengths 30–250 mm.
View product
Syringe filters
Biocomma syringe filters: nylon, PTFE, PVDF, and PES membranes in a polypropylene housing, 0.22 μm versus 0.45 μm, optional gamma-sterile.
View product
Talk to the technical team
Tell us the application. We will specify the system.
Share the workflow, capacity, and compliance constraints. We respond with a recommended configuration, not a generic catalogue list.