
Copure SPE (HLB family)
Biocomma Copure HLB: PS/DVB copolymer, pH 0–14, 500–750 m²/g, 200–400 Å, cartridges from 30 mg/1 mL to 500 mg/12 mL.
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Mixed-mode silica SPE cartridges with benzene sulfonic acid for strong cation exchange plus hydrophobic retention, for positively charged basic compounds such as amines.
Key specifications
Copure® C8/SCX Octyl / Strong Cation Exchange SPE Cartridges
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Copure® C8/SCX is a mixed-mode strong cation exchange adsorbent on a silica matrix, co-filled with benzene sulfonic acid. The negatively charged sulfonic acid groups provide strong cation exchange, while the benzene rings add hydrophobic retention. It extracts positively charged basic compounds such as amines.
The sulfonic acid has a low pKa, and its charge state can be adjusted with pH, which makes elution easier. Applications include pesticide and antibiotic residues in food such as macrolides, drugs of abuse such as amphetamines, and drugs and metabolites in biological matrices.
Specifications
7 parameters
Sulfonic acid groups with a low pKa retain positively charged basic compounds.
Benzene rings add reversed-phase retention.
The charge state of the sulfonic acid can be adjusted by pH.
Pesticide and antibiotic residues such as macrolide drugs.
Drugs of abuse such as amphetamines, and drugs and metabolites in biological matrices.
Al-Shaker specifies the configuration, documents the system, and supports it across Jordan, the GCC, and MENA.
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Share the workflow, capacity, and compliance constraints. We respond with a recommended configuration, not a generic catalogue list.